Format:
Online-Ressource
,
v.: digital
Edition:
Online-Ausg. Springer eBook Collection. Biomedical and Life Sciences Electronic reproduction; Available via World Wide Web
ISBN:
9783642103247
Series Statement:
Handbook of Experimental Pharmacology 199
Content:
The topics addressed in this volume of comparative and veterinary pharmacology, as a series of succinct state of the art reviews, illustrate both the commonality and differences between drug pharmacodynamics and pharmacokinetics in animals and man and demonstrate the potential impact of drug use in animals on human health and the environment. Genetic modification of animals and the benefits this has brought to understanding human disease and the production of drugs for use in man is considered and the potential of new technologies for improving the treatment of animal disease explored
Note:
Includes bibliographical references and index
,
Part I: Topics in Veterinary Pharmacology; Introduction; From Materia Medica to Veterinary Pharmacology and Therapeutics; Aims of This Volume and Rationale for Inclusion of the Chapters; References; Species Differences in Pharmacokinetics and Pharmacodynamics; Introduction; Diversity of Species and Breeds of Interest for Veterinary Medicine; Origin of Interspecies Differences in Modalities of Drug Administration; Origin of Interspecies Differences in Drug Disposition and Drug Action; Origin of Interspecies Differences in Dosage Regimens
,
Pour-on Formulations: Dermal or Oral Route of Administration?Consequence of Coprophagia on Drug Disposition and Responses; Interspecies Differences in Drug Disposition in Relation to Digestive Tract Physiology; Species Variation in Drug Metabolism; Kidney Function and Urinary pH; Specificity in Drug Administration and Disposition in Poultry; Species Variability in Drug Administration and Disposition in Fish; Conclusions; References; Comparative and Veterinary Pharmacogenomics; Introduction; Drug Disposition; Oxidative Enzymes; Cytochrome P450 2D15 in Dogs; Cytochrome P450 2D in Rats
,
Cytochrome P450 2C41 in DogsCytochrome P450 1A2 in Dogs; Cytochrome P450 2B11 in Dogs; Esterases in Horses and Rabbits; Conjugative Enzymes; N-acetyltransferase in Mice, Rats, Hamsters, Rabbits and Rhesus Macaques; UDP-Glucuronosyltransferase 1A in Rats; UDP-Glucuronosyltransferase 2B2 in Rats; Thiopurine Methyltransferase in Cats, Dogs and Mice; Transporters; P-glycoprotein in Dogs and Mice; MRP2 in Rats; Other; Albumin in Rats and Dogs; Arylhydrocarbon Receptor in Mice and Rats; Drug Effect; Malignant Hyperthermia in Pigs, Dogs, Cats and Horses; Warfarin Resistance in Rats
,
Future DirectionsReferences; Drug Delivery Systems in Domestic Animal Species; Introduction to Veterinary Drug Delivery: Comparison with Drug Delivery in Human Medicine; Controlled-Release Principles in Veterinary Medicine; Exogenous Regulation: Devices and Formulations; Oral Formulations; Airway Delivery: Pulmonary and Nasal; Topical Formulations and Transdermal Patches; Intravaginal Delivery for Fertility Regulation; Intramammary Formulations for Ruminants; Ocular and Periodontal Adhesives; Sustained-Release Parenteral Veterinary Drug Delivery
,
Endogenous Regulation: The Role of Drug Transporters in Regulating DeliveryABC Efflux Transporters in Veterinary Medicine; Potential Veterinary Drug Interactions Based on Transporters; Conclusions; References; Population Medicine and Control of Epidemics; Introduction; Helminth Control; Helminth Parasites of Ruminants; Helminth Parasites of Dogs and Cats; Gastro-Intestinal Nematodes; Cestodes; Heartworm; Anthelmintic Agents; Anthelmintic Resistance; Mastitis Control in Dairy Cows; Control of Respiratory Disease in Cattle and Swine; Conclusion; References; Interspecies Allometric Scaling
,
Introduction
,
Electronic reproduction; Available via World Wide Web
Additional Edition:
ISBN 9783642103230
Additional Edition:
Buchausg. u.d.T. Handbook of experimental pharmacology ; 199: Comparative and veterinary pharmacology Berlin : Springer, 2010 ISBN 9783642103230
Language:
English
Subjects:
Medicine
Keywords:
Tiermedizin
;
Pharmakologie
;
Tiermedizin
;
Pharmakologie
DOI:
10.1007/978-3-642-10324-7
URL:
Volltext
(lizenzpflichtig)
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