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  • 1
    Online-Ressource
    Online-Ressource
    Berlin, Heidelberg : Springer-Verlag Berlin Heidelberg
    UID:
    gbv_1651287198
    Umfang: Online-Ressource (VIII, 268p. 25 illus., 15 illus. in color, digital)
    ISBN: 9783642160172
    Serie: Current Topics in Microbiology and Immunology 349
    Inhalt: Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
    Inhalt: Nearly 25 years of intensive research have uncovered many diverse functions for the dimeric transcription factor known as NF-kappaB (nuclear factor-kappaB). NF-kappaB affects most aspects of cellular physiology - from immunity and inflammation to apoptosis, cell survival, growth, and proliferation
    Anmerkung: Includes bibliographical references and index , NF-jB in Health and Disease; Contents; Contributors; 99 Understanding the Logic of I kappa B:NF- kappa B Regulation in Structural Terms; 107 NF- kappa B/Rel Proteins and the Humoral Immune Responses of Drosophila melanogaster; 106 Specialized Chromatin Patterns in the Control of Inflammatory Gene Expression; 98 IKK Regulation and Human Genetics; 101 Control of NF- kappa B Activity by Proteolysis; 102 NF- kappa B and Innate Immunity; 103 NF- kappa B and Mucosal Homeostasis; 97 IKK- and NF- kappa B-Mediated Functions in Carcinogenesis; 100 Macrophages and NF- kappa B in Cancer , 104 NF- kappa B in Liver Cancer: The Plot Thickens108 NF- kappa B as a Target for Oncogenic Viruses; 105 Inhibition of NF- kappa B Signaling as a Strategy in Disease Therapy; Index
    Weitere Ausg.: ISBN 9783642160165
    Weitere Ausg.: Buchausg. u.d.T. NF-kB in health and disease Berlin : Springer, 2011 ISBN 9783642160165
    Sprache: Englisch
    Fachgebiete: Biologie
    RVK:
    Schlagwort(e): Nuklearfaktor Kappa B ; Aufsatzsammlung
    URL: Volltext  (lizenzpflichtig)
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    Online-Ressource
    Online-Ressource
    Berlin, Heidelberg :Springer Berlin Heidelberg :
    UID:
    almahu_9949419321502882
    Umfang: VIII, 268 p. , online resource.
    Ausgabe: 1st ed. 2011.
    ISBN: 9783642160172
    Serie: Current Topics in Microbiology and Immunology, 349
    Inhalt: This volume is focused on a transcription factor that started its life as a B cell-specific nuclear protein, but has matured to become one of the most extensively studied transcriptional regulators, found to control many pathophysiological processes: NF-kB. Articles in the volume, all of them written by the leading experts in the field, range from description of the NF-kB system and its basic components, its logic and its transcriptional regulatory functions to its participation in diverse processes, including inflammation, immunity, mucosal homeostasis and cancer. In addition to discussing the molecular biology and physiology of the NF-kB system, this volume also addresses the therapeutic targeting of NF-kB and its regulators. Thus, this volume is an important reading to both basic and translational scientists interested in different aspects of this highly versatile regulatory system.
    Anmerkung: Preface -- Understanding the Logic of IkappaB:NF-kappaB Regulation in Structural Terms -- IKK regulation and human genetics -- Specialized chromatin patterns in the control of inflammatory gene expression -- Macrophages and NF-kappaB in Cancer -- NF-κB/Rel proteins and the humoral immune responses of Drosophila melanogaster -- IKK and NF-kappaB mediated functions in carcinogenesis -- Control of NF-kappaB activity by proteolysis -- NF-kappaB as a target for oncogenic viruses -- NF-kappaB and Innate Immunity -- Inhibition of NF-kappaB signaling as a strategy in disease therapy -- NF-κB and mucosal homeostasis -- NF-kappaB In liver cancer - the plot thickens -- Subject index.
    In: Springer Nature eBook
    Weitere Ausg.: Printed edition: ISBN 9783642160165
    Weitere Ausg.: Printed edition: ISBN 9783642268038
    Weitere Ausg.: Printed edition: ISBN 9783642160189
    Sprache: Englisch
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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