Format:
Online-Ressource (XXII, 500 p)
,
online resource
Edition:
Springer eBook Collection. Biomedical and Life Sciences
ISBN:
9783662062746
Series Statement:
Handbook of Experimental Pharmacology 155
Content:
This volume is a review which presents both a basic science and clinical perspective on neuroprotective approaches to acute and chronic neurodegenerative conditions. Experts from both fields review current areas of neuroprotection. The book describes basic science discovery in stroke research and the application of such research within the pharmaceutical industry leading to the development of neuroprotective drugs
Note:
Section I: Mechanistic Approaches to CNS Neuroprotection: Blocking Excitotoxicity. Limiting Apoptosis as a Strategy for CNS Neuroprotection. Reducing Neuroinflammation. Mitochondrial Approaches to Neuroprotection. Stabilizing Calcium Homeostasis. Blocking Nitric Oxide ToxicitySection II: Neuroprotective Agents: Adenosine-based Approaches to the Treatment of Neurodegenerative Disease. Sodium and Calcium Channel Blockers. Neuroprotection by Free Radical Scavengers and Other Antioxidants. Chemokines and Chemokine Receptors in the CNS: New Opportunities for Novel Therapeutics in Brain Ischemia and Trauma -- Section III: CNS Delivery of Neuroprotective Therapies: Ex vivo Gene Therapy in the CNS. Developing Gene Based Neuroprotection Strategies Using Herpes Amplicon Vectors -- Section IV: Disease Targeting of Neuroprotective Therapies: Stroke. Traumatic CNS Injury. Neurohormonal Signalling Pathways and other topics.
Additional Edition:
ISBN 9783642076251
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783642076251
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783662062753
Additional Edition:
Erscheint auch als Druck-Ausgabe ISBN 9783540424123
Language:
English
DOI:
10.1007/978-3-662-06274-6
URL:
Volltext
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