UID:
almafu_9958103971502883
Umfang:
1 online resource (X + 116 pages) :
,
34 figures, 22 in color, 27 tables
Ausgabe:
1st ed.
ISBN:
9783318004021
,
3318004022
Serie:
Contributions to nephrology IgA nephropathy
Inhalt:
The author of this volume has studied IgA nephropathy for nearly 25 years, almost as long as primary IgA nephropathy has been recognized as a new disease. IgA nephropathy, considered to be an immune-complex-mediated glomerulonephri tis, is characterized by granular deposition of IgA (mainly IgA1) and C3 in the glomerular mesangial areas and is defined as nephropathy showing pro- liferative changes in the glomerular mesangial cells and increases in the mesangial matrices. Apart from being one of the most common types of chronic glomerulonephritis, it is also the most frequent case of end-stage renal disease. Since the pathogenesis of IgA nephropathy is still obscure, specific treatment is not yet available. Previous approaches have included tonsillectomy, anticoagulants, prednisolone, immunosuppressants, angiotensin-converting enzyme inhibitors and others. During his career, the author of this book has studied many aspects of IgA nephropathy, shedding much light on the mechanism of development and progression of this disease. He also undertook new treatments for patients and developed animal models for IgA nephropathy. The purpose of the present volume is to review the authors work on pathogenesis and treatment of the disease and to provide the most up-to-date findings on this subject, constituting a valuable source of information for nephrologists, general practitioners, residents and interns.
Anmerkung:
Bibliographic Level Mode of Issuance: Monograph
,
English
Weitere Ausg.:
ISBN 9783805568333
Weitere Ausg.:
ISBN 3805568339
Sprache:
Englisch
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