UID:
almafu_9958105624502883
Umfang:
1 online resource (219 p.)
ISBN:
9786610513864
,
9781280513862
,
1280513861
,
9781423796909
,
142379690X
,
9783318012941
,
3318012947
Serie:
Current directions in autoimmunity, v. 9
Inhalt:
Over the last 15 years, apoptosis has become a dominant focus of medical research in the field of immunology. This publication discusses the three major areas of apoptosis research: extrinsic death receptor pathways, intrinsic cell death pathways and the mechanisms responsible for apoptotic cell clearance. Each section delineates the proteins and signal transduction pathways and describes genetic alterations that lead to autoimmune diseases. Although most cell death abnormalities have been associated with systemic autoimmune disorders such as lupus erythematosus and lymphoproliferative syndrom
Anmerkung:
Description based upon print version of record.
,
Death receptor signaling and its function in the immune system / Fas, S.C. ... [et al.] -- Inherited and acquired death receptor defects in human autoimmune lymphoproliferative syndrome / Rieux-Laucat, F. -- Tumor necrosis factor ligand-receptor superfamily and arthritis / Hsu, H.-C., Wu, Y., Mountz, J.D. -- Mitochondria, apoptosis and autoimmunity / Pinkoski, M.J., Waterhouse, N.J., Green, D.R. -- Role of Bim and other Bcl-2 family members in autoimmune and degenerative diseases / Hughes, P., Bouillet, P., Strasser, A. -- Mitochondria, cell death, and B cell tolerance / Deming, P.B., Rathmell, J.C. -- Role of complement and other innate immune mechanisms in the removal of apoptotic cells / Ogden, C.A., Elkon, K.B. -- Collectins: opsonins for apoptotic cells and regulators of inflammation / Stuart, L.M., Henson, P.M., Vandivier, R.W. -- MFG-E8-dependent clearance of apoptotic cells, and autoimmunity caused by its failure / Hanayama, R. ... [et al.] -- Clearance of apoptotic cells in human SLE / Gaipl, U.S. ... [et al.] -- Apoptosis and glomerulonephritis / Watson, S. ... [et al.].
,
English
Weitere Ausg.:
ISBN 9783805580366
Weitere Ausg.:
ISBN 3805580363
Sprache:
Englisch
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