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  • 1
    UID:
    almafu_BV036069207
    Umfang: 1 Online-Ressource (X, 246 Seiten) : , Illustrationen, Diagramme.
    ISBN: 978-3-318-01310-8
    Serie: Contributions to microbiology Vol. 13
    Inhalt: The last two decades have shown that the local microenvironment plays a pivotal role in cancer progression. Cancer is not the result of mutation events in single cells, but of a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cytokines, chemokines and DNA-damaging agents.This book provides an up-to-date overview of how infections and chronic inflammatory conditions can give rise to the onset of a malignant phenotype, a theory that was originally postulated by Rudolf Virchow as early as 1863. Internationally recognized experts discuss novel aspects such as the role of stem cells and the occurrence of aneuploidy in carcinogenesis. Several examples of pathogens and their correlation with specific cancer types are described, e.g. Helicobacter pylori and gastric neoplasia, and schistosomiasis and bladder cancer. The mechanisms of carcinogenesis are examined in detail as are the types of cells that can transform to a malignant phenotype, with special emphasis on stem cells which have recently been shown to give rise to cancer. Further chapters discuss the role of chemokines in directing metastasis and describe options for visualizing metastasis formation in 3-dimensional model systems and in the living body.Our increasing knowledge of the inflammatory microenvironment’s role in the carcinogenic process will be the basis for investigating new anti-inflammatory strategies to counter tumor formation and growth. Therefore, this book is essential reading for scientists and clinicians working in cancer research and prevention
    Anmerkung: important new findings for anyone working in cancer research and prevention
    Weitere Ausg.: Erscheint auch als Druck-Ausgabe ISBN 978-3-8055-8064-9
    Sprache: Englisch
    Fachgebiete: Medizin
    RVK:
    Schlagwort(e): Carcinogenese ; Infektion ; Entzündung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
    Mehr zum Autor: Schmidt, Axel 1962-
    Mehr zum Autor: Zänker, Kurt S. 1946-
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 2
    Online-Ressource
    Online-Ressource
    Basel ; : Karger,
    UID:
    almafu_9958105626002883
    Umfang: 1 online resource (257 p.)
    ISBN: 9786610513895 , 9781280513893 , 1280513896 , 9781423796930 , 1423796934 , 9783318013108 , 3318013102
    Serie: Contributions to microbiology, v. 13
    Inhalt: The last two decades have shown that the local microenvironment plays a pivotal role in cancer progression. Cancer is not the result of mutation events in single cells, but of a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cytokines, chemokines and DNA-damaging agents. This book provides an up-to-date overview of how infections and chronic inflammatory conditions can give rise to the onset of a malignant phenotype, a theory that was originally postulated by Rudolf Virchow as early as 1863. Internationally recognized experts discuss novel aspects such as the
    Anmerkung: Description based upon print version of record. , In remembrance of Rudolf Virchow (1821-1902) / Schmidt, A. -- In memoriam of Rudolf Virchow: a historical retrospective including aspects of inflammation, infection and neoplasia / Schmidt, A., Weber, O.F. -- Aneuploidy and cancer: from correlation to causation / Duesberg, P. ... [et al.] -- Adult stem cell theory of the multi-stage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiated stem cells / Trosko, J.E., Tai, M.-H. -- Helicobacter pylori and gastric neoplasia / Leung, W.K. -- Schistosomiasis and neoplasia / Yosry, A. -- Relevant oncogenic viruses in veterinary medicine: original pathogens and animal models for human disease / Truyen, U., L"chelt, M. -- The inflammatory tumor microenvironment and its impact on cancer development / de Visser, K.E., Coussens, L.M. -- Co-opting macrophage traits in cancer progression: a consequence of tumor cell fusion? / Pawelek, J. ... [et al.] -- Carcinogenesis driven by bone marrow-derived stem cells / Dittmar, T. ... [et al.] -- Chemokine-directed metastasis / Gomperts, B.N., Strieter, R.M. -- Involvement of chemokine receptors in organ-specific metastasis / Zlotnik, A. -- Visualization of tumor cell extravasation / Heyder, C. ... [et al.] -- Options for visualizing metastatic disease in the living body / Helms, M.W., Brandt, B.H., Contag, C. -- Infection, inflammation and neoplasia: an interdisciplinary challenge / Zaenker, K.S. , English
    Weitere Ausg.: ISBN 9783805580649
    Weitere Ausg.: ISBN 3805580649
    Sprache: Englisch
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
  • 3
    UID:
    gbv_64067075X
    Umfang: Online-Ressource
    Ausgabe: Reproduktion Karger eBooks Collection 1997-2009
    ISBN: 9783318013108
    Serie: Contributions to microbiology 13
    Inhalt: The last two decades have shown that the local microenvironment plays a pivotal role in cancer progression. Cancer is not the result of mutation events in single cells, but of a complex interplay of tumor cells, inflammatory cells, stem cells, growth factors, cytokines, chemokines and DNA-damaging agents.This book provides an up-to-date overview of how infections and chronic inflammatory conditions can give rise to the onset of a malignant phenotype, a theory that was originally postulated by Rudolf Virchow as early as 1863. Internationally recognized experts discuss novel aspects such as the role of stem cells and the occurrence of aneuploidy in carcinogenesis. Several examples of pathogens and their correlation with specific cancer types are described, e.g. Helicobacter pylori and gastric neoplasia, and schistosomiasis and bladder cancer. The mechanisms of carcinogenesis are examined in detail as are the types of cells that can transform to a malignant phenotype, with special emphasis on stem cells which have recently been shown to give rise to cancer. Further chapters discuss the role of chemokines in directing metastasis and describe options for visualizing metastasis formation in 3-dimensional model systems and in the living body.Our increasing knowledge of the inflammatory microenvironment’s role in the carcinogenic process will be the basis for investigating new anti-inflammatory strategies to counter tumor formation and growth. Therefore, this book is essential reading for scientists and clinicians working in cancer research and prevention
    Anmerkung: Includes bibliographical references and indexes , Cover; Contents; In Remembrance of Rudolf Virchow (1821-1902); Foreword; General Aspects; Specific Pathogens; Infection, Inflammation and Neoplasia; Chemokine-Directed Metastasis; Outlook and Perspectives; Author Index; Subject Index
    Weitere Ausg.: ISBN 9783805580649
    Weitere Ausg.: Erscheint auch als Druck-Ausgabe Infection and inflammation Basel : Karger, 2006 ISBN 3805580649
    Sprache: Englisch
    Fachgebiete: Medizin
    RVK:
    Schlagwort(e): Carcinogenese ; Infektion ; Entzündung ; Aufsatzsammlung
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
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