UID:
edoccha_9959076721302883
Umfang:
1 online resource (140 p.)
ISBN:
1-283-15354-8
,
9786613153548
,
3-8055-9225-6
Serie:
World review of nutrition and dietetics,
Inhalt:
For more than half a century, the relationship between dietary factors and coronary heart disease (CHD) has been a major focus of health research. Contrary to the established view, current data suggest that dietary cholesterol is not a primary factor of or causes heart disease - with the possible exception of the genetic forms of familial hypercholesterolemias. For instance, recent clinical trials evaluating the effect of cholesterol-lowering drugs on the development of chronic heart failure, diabetes and stroke have yielded disappointing results. On the other hand, an unbalanced omega-6/omega-3 fatty acid ratio and a cholesterol intake not consistent with the amount during evolution seem to be causal factors in the development of CHD. A panel of international experts in genetics, nutrition, fatty acid, cholesterol, metabolism and coronary heart disease has contributed to this publication, summarizing and critically discussing for the first time the importance of evolutionary aspects of diet, the omega-6/omega-3 fatty acid ratio and cholesterol intake relative to health and CHD. They also propose measuring blood fatty acids in the population in order to define the risk of CHD and other chronic diseases. This book will be of interest to physicians (cardiologists, gerontologists, and pediatricians), nutritionists, dieticians, health care providers, scientists in industry and government and policy makers.
Anmerkung:
"... presentations from the satellite workshop of the Second Congress of the International Society of Nutrigenetics/Nutrigenomics that took place in Geneva on October 6-8, 2008. The satellite workshop held on October 9, 2008, was the 6th International Congress on the Columbus Concept ..."--Preface.
,
""Cover""; ""Contents""; ""List of Contributors""; ""Preface""; ""Evolutionary Aspects of the DietaryOmega�6: Omega�3 Fatty Acid Ratio: Medical Implications""; ""Imbalance of Omega�6/Omega�3 fatty acids""; ""Biological Effects and the Omega�6:Omega�3 Ratio""; ""Mechanisms""; ""The Balance of Omega�6/Omega�3 Fatty Acids Is Important for Health: The Evidence from Gene Transfer Studies""; ""Omega�3 Fatty Acids and Gene Expression""
,
""Linoleic Acid and Arachidonic Acid Increase Atherogenesis: Evidence from Diet-Gene Interactions: Genetic Variation and Omega�6 and Omega�3 Fatty Acid Intake and the Risk for Cardiovascular Disease""""Omega�3 Fatty Acids and the Brain""; ""Conclusions and Recommendations""; ""References""; ""Measuring Blood Fatty Acids as a Surrogate Indicator for Coronary Heart Disease Risk in Population Studies""; ""Connect the Dots""; ""Describing Balanced and Imbalanced HUFA Proportions""; ""Competitive Hyperbolic Interactions Maintain Tissue HUFA""; ""Dietary Reference Intakes""
,
""First ... Kill All the Lawyers (Shakespeare, King Henry VI, Act 4, Scene 2)""""References""; ""Fast Determination of Fatty Acids in Whole Blood Collected from Fingertips: Application to the Assessment of Fatty Acid Patterns (and Various Indexes) in Population Studies""; ""Method""; ""Applications""; ""Discussion and Conclusions""; ""References""; ""Evolution and Cholesterol""; ""Serum Cholesterol Concentrations""; ""Diet and Serum Cholesterol Concentrations""; ""Conclusion""; ""References""; ""Dietary Cholesterol and Blood Cholesterolemia: A Healthy Relationship""; ""Animal Studies""
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""Epidemiological Surveys""""Clinical Trials""; ""Egg Intake and Heart Disease Risk""; ""Benefits of Dietary Cholesterol""; ""Conclusions""; ""References""; ""Blood Cholesterol as a Good Marker of Health in Japan""; ""Subjects and Methods""; ""Results""; ""Discussion""; ""Acknowledgements""; ""References""; ""Cholesterol and Skeletal Muscle Health""; ""Skeletal Muscle and Health""; ""The Effect of Exercise on Blood Cholesterol""; ""Skeletal Muscle Contraction and Cholesterol Metabolism""; ""Potential Mechanism for Anabolic Effects of Cholesterol on Skeletal Muscle""
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""Statins and Skeletal Muscle Health""""Summary""; ""References""; ""Disappointing Recent Cholesterol-Lowering Drug Trials: Is It Not Time for a Full Reappraisal of the Cholesterol Theory?""; ""The ENHANCE Study""; ""SEAS and GISSI-HF""; ""The JUPITER Trial""; ""Conclusion""; ""References""; ""Cholesterol Was Healthy in the End""; ""The Effect of Saturated Fat on Blood Cholesterol""; ""The Effect of Saturated Fat on Cardiovascular Disease""; ""The Effect of High Cholesterol on Atherosclerosis""; ""The Effect of High Cholesterol on Cardiovascular Disease""
,
""The Effect of High Cholesterol in Familial Hypercholesterolemia""
,
English
Weitere Ausg.:
ISBN 3-8055-9224-8
Sprache:
Englisch
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