Kooperativer Bibliotheksverbund

UID:

Format: 1 online resource (252 p.)

Edition: 1st ed.

ISBN: 92-4-068042-X , 9786610011650 , 1-280-01165-3

Content: This report is intended to highlight the relevance of genomics (the study of genomes) for health care worldwide, with a particular focus on its potential for improving health in developing countries. The application of knowledge gained from the characterization of the genomes of several organisms, including the human genome, holds considerable potential for the development of new health care innovations over the coming decades. This new field, however, presents a series of highly complex scientific, economic, social and ethical issues which must be taken into account if the genomic revolution

Note: Description based upon print version of record. , ""Contents""; ""Executive Summary""; ""1. Introduction""; ""2. Genomics and the Genome Projects""; ""2.1 Introduction""; ""2.2 What are genes and how do they function?""; ""2.3 The development of molecular genetics""; ""2.3.1 Classical genetics""; ""2.3.2 Molecular genetics""; ""2.4 Characterizing the human genome""; ""2.4.1 The identification of human disease genes""; ""2.4.2 The Human Genome Project""; ""2.4.3 Mapping the human genome""; ""2.5 Functional genomics""; ""2.5.1 Annotation of the human genome""; ""2.5.2 Proteomics""; ""2.5.3 Transcriptomics""; ""2.5.4 Gene regulation"" , ""2.5.5 Bioinformatics""""2.6 The genomes of other organisms""; ""2.6.1 Introduction""; ""2.6.2 The pathogen genome project""; ""2.6.3 The genomics of disease vectors""; ""2.6.4 The genomes of the worm, fruitfly, yeast and various animals""; ""2.6.5 The central importance of the mouse genome project""; ""2.6.6 Plant genomics""; ""2.7 Summary""; ""3. The Potential of Genomics for Health Care""; ""3.1 Introduction""; ""3.2 Monogenic disease""; ""3.3 Communicable disease""; ""3.4 Cancer""; ""3.5 Complex multifactorial disease""; ""3.6 Developmental abnormalities and mental retardation"" , ""3.7 Ageing""""3.8 Pharmacogenomics""; ""3.9 Gene therapy""; ""3.10 Stem cell therapy""; ""3.11 Plant genomics and human health""; ""3.12 Forensic medicine""; ""3.13 Biotechnology""; ""3.14 Broader issues of biology""; ""3.15 Summary""; ""4. Relevance and Time-Scale of Advances in Genomics for Global Health""; ""4.1 Genomics in the context of current world health problems""; ""4.2 When will the medical promises of genomics be fulfilled?""; ""4.3 Maintaining the balance of research planning and health care""; ""4.4 Will the medical applications of genome research be affordable?"" , ""5.5 Forging international partnerships in academia""""5.6 Regional collaboration""; ""5.7 Information technology and bioinformatics""; ""5.8 Summary and future possibilities""; ""6. Potential Risks and Hazards of the Applications of Genomics and Their Control""; ""6.1 Introduction""; ""6.2 Genetic manipulation""; ""6.3 Risks in non-human genomics""; ""6.3.1 Animals and insects""; ""6.3.2 Plants""; ""6.4 Changing the genetic constitution of individuals or populations""; ""6.5 Genetic databases""; ""6.6 Biological warfare and other political misuses""; ""6.7 Stem cell gene therapy"" , ""6.8 Summary"" , English

Additional Edition: ISBN 92-4-154554-2

Additional Edition: ISBN 0-585-46938-5

Language: English