UID:
almahu_9948026027802882
Umfang:
1 online resource (453 p.)
ISBN:
1-281-01159-2
,
9786611011598
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0-08-049481-1
Inhalt:
DescriptionAlthough most strains of E. coli bacteria are harmless and live in the intestines of healthy humans and animals, several strains can produce powerful toxins and cause severe illness in humans. This versatile pathogen is best known for being transmitted to humans through contaminated foods - such as undercooked meat and unpasteurized fruit juice - and has attracts much attention when serious outbreaks occur.Importance of TopicE. coli is capable of causing a wide variety of diseases - from urinary tract infections to meningitis. A considerable amount of m
Anmerkung:
Description based upon print version of record.
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Front Cover; Escherichia coli: Virulence Mechanisms of a Versatile Pathogen; Copyright Page; Contents; Part II: Escherichia coli Pathotypes; Part III: Escherichia coli Virulence Factors; Contributors; Introduction; Part I: Escherichia coli The Organism; Chapter 1. The Genomes of Escherichia coli K-12 and Pathogenic E. coli; Introduction; History of E. coli Genomics; Analysis and Comparison of E. coli Genomes; Functional Analyses of E. coli Genes; The Future of E. coli Genomics; Acknowledgments; References; Chapter 2. Evolution of Pathogenic Escherichia coli; Introduction
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Evolution in E. coliVirulence Factors and Virulence; Phylogenetic Relationships in E. coli; Evolution of Individual VFs; Diversifying and Directional Selection; Phylogenetic Distribution of VFs; Pathogenicity-Associated Islands; Virulence Plasmids; Repeated Emergence of Virulent Clones; Genomic Background and Virulence; Phylogenetic Distribution of Pathogenic E. coli; Intestinal Pathogenic E. coli; Why Pathogenic E. coli?; Summary; Acknowledgments; References; Chapter 3. Enteropathogenic Escherichia coli; Characteristics of EPEC and EPEC Infections; EPEC Molecular Pathogenesis
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Integration of EPEC Pathogenic FeaturesDiagnosis, Prevention, and Control of EPEC Infections; References; Chapter 4. Enterohemorrhagic and Other Shiga Toxin-Producing Escherichia coli; Background; Epidemiology of STEC; Clinical Manifestations of STEC Infection; Shiga Toxins; Molecular Pathogenesis; HUS Pathogenesis and Effects of Shiga Toxin on Various; Prospects for Prevention and Control; References; Chapter 5. Enterotoxigenic Escherichia coli; ETEC Epidemiology; ETEC Pathogenesis; ETEC Virulence Factors; Treatment and Prevention of ETEC Infections; References
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Chapter 6. Enteroaggregative and Diffusely Adherent Escherichia coliEnteroaggregative E. coli; Diffusely Adhering E. coli; References; Chapter 7. Shigella and Enteroinvasive Escherichia coli: Paradigms for Pathogen Evolution and Host-Parasite Interactions; Introduction; Classification and Biochemical Characteristics; Characteristics of Disease; Virulence Factors and Genetics; Evolution of Shigella Species and EIEC; Conclusions; Acknowledgments; References; Chapter 8. Uropathogenic Escherichia coli; Epidemiology and Clinical Symptoms; UPEC as a Defined Group of Strains; Virulence Factors
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ModelSummary; References; Chapter 9. Meningitis-Associated Escherichia coli; Introduction; Models of Blood-Brain Barrier; A Threshold Level of Bacteremia; Bacterial Structures Contributing to Binding to BMECs; Bacterial Structures Contributing to Invasion of BMECs; E. coli K1 Genome; Bacterial Trafficking of BMEC; Traversal of the Blood-Brain Barrier as Live Bacteria; Conclusion; Acknowledgments; References; Chapter 10. Adhesive Pili of the Chaperone-Usher Family; Introduction; Characteristics of Pili; Biogenesis of Pili; Conclusion; Acknowledgments; References; Chapter 11. Type IV Pili
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Introduction
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English
Weitere Ausg.:
ISBN 0-12-220751-3
Sprache:
Englisch
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