Kooperativer Bibliotheksverbund

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Umfang: 1 online resource (503 p.)

ISBN: 1-281-01202-5 , 9786611012021 , 0-08-049737-3

Inhalt: Neurobiology of Addiction is conceived as a current survey and synthesis of the most important findings in our understanding of the neurobiological mechanisms of addiction over the past 50 years. The book includes a scholarly introduction, thorough descriptions of animal models of addiction, and separate chapters on the neurobiological mechanisms of addiction for psychostimulants, opioids, alcohol, nicotine and cannabinoids. Key information is provided about the history, sources, and pharmacokinetics and psychopathology of addiction of each drug class, as well as the behavioral and neur

Anmerkung: Description based upon print version of record. , Front Cover; Neurobiology of Addiction; Copyright Page; Contents; Preface; Acknowledgments; Chapter 1. What is Addiction; Definitions of addiction; Neuroadaptational Views of Addiction; Summary; References; Chapter 2. Animal Models of Drug Addiction; Definitions and Validation of Animal Models; Animal Models for the Binge/Intoxication Stage of the Addiction Cycle; Animal Models for the Drug Withdrawal/Negative Affect Stage of the Addiction Cycle; Animal Models for the Preoccupation/Anticipation (Craving) Stage of the Addiction Cycle; Animal Models for the Transition to Addiction; Summary , ReferencesChapter 3. Psychostimulants; Definitions; History of Psychostimulant Use, Abuse, and Addiction; Behavioral Effects and Medical Uses; Pharmacokinetics; Abuse and Addiction Potential; Behavioral Mechanisms; Neurobiological Mechanism-Neurocircuitry; Neurobiological Mechanism-Cellular; Neurobiological Mechanism-Molecular; Summary; References; Chapter 4. Opioids; Definitions; History of Opioid Use, Abuse, and Addiction; Medical Use and Behavioral Effects; Pharmacokinetics; Abuse and Addiction Potential; Behavioral Mechanism of Action; Neurobiological Mechanism-Neurocircuitry , Neurobiological Mechanism-CellularNeurobiological Mechanism-Molecular; Summary; References; Chapter 5. Alcohol; Definitions; History of Alcohol Use, Abuse, and Alcoholism; Behavioral Effects of Alcohol; Pharmacokinetics; Abuse and Addiction Potential; Behavioral Mechanism of Action; Neurobiological Mechanism-Neurocircuitry; Neurobiological Mechanism-Cellular; Neurobiological Mechanism-Molecular; Summary; References; Chapter 6. Nicotine; Definitions; History of Tobacco Use, Abuse, and Addiction; Medical Use and Behavioral Effects; Pharmacokinetics; Abuse and Addiction Potential , Behavioral Mechanism of ActionNeurobiological Mechanism-Neurocircuitry; Neurobiological Mechanism-Cellular; Neurobiological Mechanism-Molecular; Summary; References; Chapter 7. Cannabinoids; Definitions; History of Cannabinoid Use, Abuse, and Addiction; Medical Use and Behavioral Effects; Pharmacokinetics; Cannabinoid Tolerance; Cannabinoid Withdrawal; Pathology and Psychopathology; Behavioral Mechanism of Action; Neurobiological Mechanism-Neurocircuitry; Neurobiological Mechanism-Cellular; Neurobiological Mechanism-Molecular; Summary; References; Chapter 8. Imaging; Introduction , Basic Technical Principles of NeuroimagingBrain Imaging of Drug Addiction; Integration of Imaging Studies in Humans with the Neurocircuitry of Addiction; Summary; References; Chapter 9. Neurobiological Theories of Addiction; Introduction; Neurocircuitry Hypotheses of Addiction Dopamine and Reward; Neurocircuitry Theories of Addiction-Executive Function; Neurocircuitry Theories of Addiction-Relapse; Neurocircuitry Theories of Addiction-Reward and Stress; Cellular Hypotheses of Addiction; Molecular Hypotheses of Addiction; Synthesis: Common Elements of Most Neurobiological Models of Addiction , References , English

Weitere Ausg.: ISBN 0-12-419239-4

Sprache: Englisch