Kooperativer Bibliotheksverbund

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Format: 1 online resource (537 pages) : , illustrations

Edition: 1st ed.

ISBN: 1-281-03438-X , 9786611034382 , 1-4356-0490-3 , 0-08-053858-4

Series Statement: Handbook of chemical neuroanatomy ; v. 16

Content: During the last few years, the pace of research in the field of neuropeptide receptors has increased steadily: new neuropeptides were discovered, and the classification of receptor subtypes has been refined. It thus appeared essential to update the information. Peptide Receptors Part I summarizes current knowledge on ten distinct peptide families. This volume integrates photomontages and maps of quantitative receptor autoradiography, in situ hybridization histochemistry, and immunocytochemistry images.

Note: Description based upon print version of record. , Cover; TOCContents; List of Contributors; Preface; Chapter I. Somatostatin receptors; 1. Introduction; 2. Structural and biochemical properties; 3. Localization of somatostatin binding sites in the central nervous system; 4. Localization of somatostatin receptor subtypes; 5. Somatostatin receptors in brain disorders; 6. Perspectives; 7. Abbreviations; 8. Acknowledgements; 9. References; Chapter II. Brain PACAP/VIP receptors: regional distribution, functional properties and physiological relevance; 1. Introduction; 2. Distribution of VIP and PACAP receptors , 3. Molecular cloning and pharmacological characterization of VIP/PACAP receptors4. Signal transduction; 5. Trophic actions of VIP and PACAP; 6. Involvement of VIP/PACAP in circadian rhythms and sleep; 7. Regulation of brain energy metabolism by VIP; 8. Modulation by VIP and PACAP of glutamate-mediated signalling in the cerebral cortex; 9. Abbreviations; 10. Acknowledgements; 11. References; Chapter III. Localization of angiotensin receptors in the nervous system; 1. Introduction; 2. Localization of AT1 and AT2 receptors; 3. Overview of AT1 receptor functions in selected brain regions , 4. Conclusion; 5. Abbreviations; 6. Acknowledgements; 7. References; Chapter IV. Brain endothelin and natriuretic peptide receptors; 1. Why endothelin and natriuretic receptors?; 2. Brain endothelin receptors; 3. Brain natriuretic peptide receptors; 4. References; Chapter V. Neuropeptide FF receptors; 1. Introduction; 2. Pharmacological activities of neuropeptide FF; 3. Neuropeptide FF as a neurotransmitter; 4. Neuropeptide FF receptors; 5. Brain neuropeptide FF receptors in other species; 6. Discussion; 7. Abbreviations; 8. Acknowledgements; 9. References , Chapter VI. Neurokinin receptors in the CNS; 1. Introduction; 2. Discovery of the tachykinins; 3. Distribution of tachykinin-like immunoreactivity; 4. Physiological functions of tachykinins; 5. CNS neurokinin receptors; 6. Are tachykinins mostly involved in 'volume' transmission?; 7. Conclusion; 8. Abbreviations; 9.Acknowledgements; 10. References; Chapter VII. Brain kallikrein-kinin system: from receptors to neuronal pathways and physiological functions; 1. Introduction; 2. The kallikrein-kinin system; 3. Regional distribution of the kallikrein-kinin system in the central nervous system , 4. On the physiological role for kinins in central cardiovascular regulation; 5. On the physiological role for kinins in the spinal cord; 6. Other central effects of kinins; 7. Considerations and perspectives; 8. Conclusion; 9. Abbreviations; 10. Acknowledgements; 11. References; Chapter VIII. Calcitonin gene-related peptide (CGRP), amylin and adrenomedullin: anatomical localization and biological functions in the mammalian and human brains; 1. Discovery and genomic composition; 2. Structure of CGRP and structure-activity relationships; 3. Amylin; 4. Adrenomedullin; 5. Neuroanatomical localization , English

Additional Edition: ISBN 0-444-82972-5

Language: English