UID:
almafu_9958130986702883
Umfang:
1 online resource (348 p.)
ISBN:
1-281-03750-8
,
9786611037505
,
0-08-054584-X
Serie:
Progress in brain research, v. 145
Inhalt:
Comprehensive exposé, by leading neuroscientists, of current knowledge on the neurotransmitter acetylcholine in the cerebral cortex. All aspects of the subject are covered, from its most elementary, at the molecular and cellular levels, to its systemic and holistic implications, including its role in cognition and involvement in human diseases and therapeutics. The twenty-two chapters are grouped under four main headings : I. Functional Morphology of the Acetylcholine Innervation in Cerebral Cortex (Including Hippocampus); II. Modes of Action of Acetylcholine in the Cerebral Corte
Anmerkung:
Description based upon print version of record.
,
Front Cover; Acetylcholine in the Cerebral Cortex; Copyright Page; List of Contributors; Preface; Acknowledgments; Contents; Section I: The acetylcholine innervation of cerebral cortex; Chapter 1. Phylogenetic and ontogenetic aspects of the basal forebrain cholinergic neurons and their innervation of the cerebral cortex; Chapter 2. Structural determinants of the roles of acetylcholine in cerebral cortex; Chapter 3. Muscarinic acetylcholine receptor subtypes in cerebral cortex and hippocampus; Chapter 4. The cholinergic innervation of the human cerebral cortex
,
Section II: Modes of action of acetylcholine in the cerebral cortexChapter 5. Synaptic mechanisms modulated by acetylcholine in cerebral cortex; Chapter 6. Functional and molecular characterization of neuronal nicotinic ACh receptors in rat hippocampal interneurons; Chapter 7. The nicotinic acetylcholine receptor subtypes and their function in the hippocampus and cerebral cortex; Chapter 8. Studies of muscarinic neurotransmission with antimuscarinic toxins; Section III: Cortical properties and functions modulated by acetylcholine
,
Chapter 9. Hyperactivation of developing cortical circuits by acetylcholine and the ontogeny of abnormal cognition and emotion: findings and hypothesisChapter 10. Synaptic mechanisms and cholinergic regulation in auditory cortex; Chapter 11. Activity, modulation and role of basal forebrain cholinergic neurons innervating the cerebral cortex; Chapter 12. Cholinergic modulation of the cortical microvascular bed; Chapter 13. Acetylcholine systems and rhythmic activities during the waking-sleep cycle; Chapter 14. Cholinergic mechanisms mediating anesthetic induced altered states of consciousness
,
Chapter 15. High acetylcholine levels set circuit dynamics for attention and encoding and low acetylcholine levels set dynamics for consolidationSection IV: Clinical, pathological and therapeutic implications; Chapter 16. Knockout and knockin mice to investigate the role of nicotinic receptors in the central nervous system; Chapter 17. Nicotinic modulation of thalamocortical neurotransmission; Chapter 18. Amyloid ß peptides and central cholinergic neurons: functional interrelationship and relevance to Alzheimer's disease pathology; Chapter 19. Nicotinic receptor mutations in human epilepsy
,
Chapter 20. Neurochemistry of consciousness: cholinergic pathologies in the human brainChapter 21. Functional studies of cholinergic activity in normal and Alzheimer disease states by imaging technique; Chapter 22. Paying attention to acetylcholine: the key to wisdom and quality of life?; Subject Index
,
English
Weitere Ausg.:
ISBN 0-444-51125-3
Sprache:
Englisch
Bookmarklink
