Kooperativer Bibliotheksverbund

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Umfang: 1 online resource (xv, 520 pages) : , illustrations (chiefly color)

ISBN: 1-281-10001-3 , 9786611100018 , 0-08-055677-9

Inhalt: Ocular Therapeutics: Eye on New Discovery focuses on emerging areas in ocular research, from new approaches to dry eye to gene therapy in the management of retinal diseases. This comprehensive book features more than 25 chapters of information that will be vital for ocular investigators and ophthalmologists bringing them new information on promising therapeutics.

Anmerkung: FRONT COVER; OCULAR THERAPEUTICS; COPYRIGHT PAGE; CONTENTS; CONTRIBUTORS; PREFACE; SECTION I. GENERAL PRINCIPLES AND THERAPEUTIC TARGETS; Chapter 1. The Eye as a Drug Target; Chapter 2. Drug Delivery Systems in Ophthalmic Applications; I. Introduction; II. Mechanics of Delivery Systems and Their Administration; III. Delivery Systems for Ocular Disease; IV. Conclusions; V. References; Chapter 3. IOP as a Target - Inflow and Outflow Pathways; I. Glaucoma: IOP as a Risk Factor; II. Basic Mechanisms of Aqueous Hydrodynamics; III. Overview of Currently Available Glaucoma Medications , IV. Prostaglandin Analogs (PGAs); V. β-Blockers; VI. α[sub(2)]-Agonists; VII. Topical Carbonic Anhydrase Inhibitors; VIII. Cholinergics; IX. Epinephrine and Analogs; X. Recent Development in Future Ocular Hypotensive Medications; XI. Cytoskeleton Acting Agents; XII. Protein Kinase Inhibitors; XIII. Statins; XIV. Serotonergic Agonists; XV. Activators of Extracellular Matrix Hydrolysis; XVI. Compounds that Increase Cyclic GMP; XVII. Cannabinoids; XVIII. Identification of New Therapeutic Targets Based on Understanding Disease Pathogenesis; XIX. Conclusions; XX. References , Chapter 4. The Ciliary Body: A Potential Multifaceted Functional Neuroendocrine Unit; I. Introduction; II. Ciliary Epithelial Peptides and Aqueous Flow; III. New Frontiers of Ciliary Body Research: Retinal Progenitor Cells and Ocular Stem Cells; IV. Acknowledgments; V. References; Chapter 5. Growth Factors and Neurotrophic Factors as Targets; I. Growth Factors; II. Expression and Function of Growth Factors in Ocular Tissues; III. References; SECTION II. VISUAL PATHWAY; Chapter 6. New Therapies for Dry Eye Disease; I. Introduction; II. Historical Perspective , III. Enhanced Tear Stabilizers and Ocular Surface Protectants; IV. Anti-Inflammatory Medications; V. Conclusion; VI. References; Chapter 7. Refractive Surgery - Corneal Opacity (Haze) after Surface Ablation; I. Clinical Disease; II. Clinical Objectives; III. Basic Mechanisms; IV. Current Therapy; V. Future Therapy; VI. Summary; VII. Acknowledgments; VIII. References; Chapter 8. Progress in Preventing Age-Related Cataract; I. Introduction; II. Age-Related Cataract: At Least Three Different Diseases; III. Causality and Cataracts; IV. Investigating Cataracts , V. The Influence of the Intraocular Environment on Cataract Formation; VI. Risk Factors for Age-Related Cataracts; VII. Final Thoughts; VIII. References; Chapter 9. Myopia Pharmacology: Etiologic Clues, Therapeutic Potential; I. Introduction; II. Clinical Myopia; III. Why Myopia?; IV. Basic Research Approaches to Studying Myopia Pathogenesis; V. Pharmacology as an Approach to Myopia Pathogenesis; VI. Pharmacology of Myopia; VII. Eyes with Non-Restricted Vision; VIII. Concluding Thoughts; IX. Acknowledgments; X. References; SECTION III. INFLAMMATION, IMMUNE SYSTEM AND ANTI-INFECTIVES; Chapter 10. Immune System and the Eye , English

Weitere Ausg.: ISBN 0-12-370585-1

Sprache: Englisch