Format:
Online-Ressource (XXIII, 1095p, digital)
ISBN:
9789400702653
Series Statement:
Advances in Experimental Medicine and Biology 704
Content:
Transient Receptor Potential Channels is a unique blend of thoughtfully selected topics ranging from the structural biology of this fascinating group of ion channels to their emerging roles in human diseases. TRP channels of yeasts, flies, parasites, fishes, frogs and human are all included in one and the same book. From biophysics of primary thermo-sensory events in cells to thermosensation at whole organism level, from physiology of pain to development of pain-killers, from psychiatric illnesses to cancers, from skin cells to sperms, from taste buds to testes, from established facts to heated debates, this book contains something for every TRP enthusiasts, beginners as well as experts. It contains crucial background information, critical analysis of cutting edge research, ideas and thoughts for numerous testable hypotheses and shows directions for future research in this highly dynamic field. It is a book that one would love to possess oneself and would love to give away to someone one likes.
Note:
Includes bibliographical references and index
,
Preface; References; Contents; Contributors; 1 Structural Biology of TRP Channels; References; 2 Functional and Structural Studies of TRP Channels Heterologously Expressed in Budding Yeast; References; 3 Natural Product Ligands of TRP Channels; References; 4 Synthetic Modulators of TRP Channel Activity; References; 5 Study of TRP Channels by Automated Patch Clamp Systems; References; 6 TRPC2: Of Mice But Not Men; References; 7 TRPM1: New Trends for an Old TRP; References; 8 The Non-selective Monovalent Cationic Channels TRPM4 and TRPM5; References
,
9 TRPM7, the Mg 2+ Inhibited Channel and KinaseReferences; 10 TRPM8 in Health and Disease: Cold Sensing and Beyond; References; 11 TRPML1; References; 12 TRPML2 and the Evolution of Mucolipins; References; 13 The TRPML3 Channel: From Gene to Function; References; 14 TRPV5 and TRPV6 in Transcellular Ca 2 +Transport: Regulation, Gene Duplication, and Polymorphisms in African Populations; References; 15 The TRPV5 Promoter as a Tool for Generation of Transgenic Mouse Models; References; 16 TRPP Channels and Polycystins; References; 17 TRP Channels in Yeast; References; 18 C. elegans TRP Channels
,
References19 Investigations of the In Vivo Requirements of Transient Receptor Potential Ion Channels Using Frog and Zebrafish Model Systems; References; 20 TRP Channels in Parasites; References; 21 Receptor Signaling Integration by TRP Channelsomes; References; 22 Gating Mechanisms of Canonical Transient Receptor Potential Channel Proteins: Role of Phosphoinositols and Diacylglycerol; References; 23 The TRPC Ion Channels: Association with Orai1 and STIM1 Proteins and Participation in Capacitative and Non-capacitative Calcium Entry; References
,
24 Contribution of TRPC1 and Orai1 to Ca 2+ Entry Activated by Store DepletionReferences; 25 Primary Thermosensory Events in Cells; References; 26 Thermo-TRP Channels: Biophysics of Polymodal Receptors; References; 27 Complex Regulation of TRPV1 and Related Thermo-TRPs: Implications for Therapeutic Intervention; References; 28 Voltage Sensing in Thermo-TRP Channels; References; 29 TRP Channels as Mediators of Oxidative Stress; References; 30 Regulation of TRP Signalling by Ion Channel Translocation Between Cell Compartments; References
,
31 Emerging Roles of Canonical TRP Channels in Neuronal FunctionReferences; 32 TRP Channels and Neural Persistent Activity; References; 33 Role of TRP Channels in Pain Sensation; References; 34 TRPV1: A Therapy Target That Attracts the Pharmaceutical Interests; References; 35 Expression and Function of TRP Channels in Liver Cells; References; 36 Expression and Physiological Roles of TRP Channels in Smooth Muscle Cells; References; 37 TRPM Channels in the Vasculature; References
,
38 Molecular Expression and Functional Role of Canonical Transient Receptor Potential Channels in Airway Smooth Muscle Cells
Additional Edition:
ISBN 9789400702646
Additional Edition:
Buchausg. u.d.T. Transient receptor potential channels Dordrecht [u.a.] : Springer, 2011 ISBN 9789400702646
Language:
English
Subjects:
Biology
Keywords:
Ionenkanal
;
Ionenkanal
DOI:
10.1007/978-94-007-0265-3
URL:
Volltext
(lizenzpflichtig)
Bookmarklink
