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  • 1
    Online-Ressource
    Online-Ressource
    Dordrecht : Springer Science+Business Media B.V
    UID:
    gbv_1651289077
    Umfang: Online-Ressource (VI, 235p. 85 illus., 8 illus. in color, digital)
    ISBN: 9789400711341
    Serie: SpringerLink
    Inhalt: "Mobility and Environment calls for a mobility revolution which does not simply mean taking a bus instead of a car: it implies a dramatic shift in the political debate from a technical to a political culture. The author introduces his book by disputing ""non-political"" Sustainable Development policies which are among the major culprits for the conservatism in environmental policies. For at least forty years, urban mobility policies, based on compulsive infrastructure building, have failed both in satisfying transportation demand and in coping with high environmental impacts. Nonetheless decision-makers keep employing the same professionals and therefore they act as shepherds who commit their sheep in the wolf's custody. Corrado Poli treats mobility policy as a political, ethical, social and educational issue rather than as a mere civil engineering one. Mobility and Environment challenges some deeply entrenched professional and economic monopolies which negatively affect urban and transportation planning in North America and Europe, and argues the old idea which bounded transportation and communication. A real environmentalist effort in traffic planning should begin from new technologies and from the analysis of citizens preferences. A series of new projects are presented which include mobility demand reduction and focus on democracy in planning. "
    Anmerkung: Includes bibliographical references and index , Cell Death in Mammalian Ovary; Contents; Part IIntroduction; Chapter 1: Brief Description of the Histological, Cytological and Functional Aspects of the Ovary; 1.1 Morphological Characteristics of the Ovary; 1.2 Molecular Factors Regulate the Function of the Ovary; 1.3 Hormonal Aspects of the Ovarian Functions; References; Chapter 2: Embryonic Development of the Ovary, Sexual Reproduction and Meiosis; 2.1 Evolutionary Advantages of Sexual Reproduction; 2.2 Strategies for PGC Formation; 2.3 Molecular Mechanisms of PGC Specification in Mouse; 2.4 PGC Migration; 2.5 Formation of the Ovary , 2.6 Germ Cell Sex2.7 Endocrine and Paracrine Regulation of Folliculogenesis; 2.8 The Meiotic Division; 2.9 Epigenetic Reprogramming of Germ Cells; References; Chapter 3: Development of the Ovary in the Embryo, Infancy, Childhood, Pre-puberty and Puberty; 3.1 Infancy; 3.2 Childhood; 3.2.1 Puberty; References; Part IIGeneral Aspects of Cell Death; Chapter 4: Apoptosis; List of Abbreviations; 4.1 General Characteristics of the Apoptosis; 4.2 Caspases; 4.3 Bcl2 Proteins; 4.4 Extrinsic Route of Caspases Activation; 4.5 Intrinsic Apoptosis Activation , 4.6 Crosslinking Between Extrinsic and Intrinsic Activation4.7 Apoptosis-Inducing Factor (AIF); 4.8 Inhibitor of Apoptosis Proteins (IAPs); 4.9 Execution Phase; 4.10 Other Routes of Apoptosis Activation; References; Chapter 5: Autophagy; List of Abbreviations; 5.1 Autophagy Process; 5.2 Macroautophagy; 5.3 Microautophagy; 5.4 Chaperone-Mediated Autophagy System; 5.5 Atg Genes; 5.6 Atg9 Cycling System; 5.7 Class-III PI3K; 5.7.1 Ubiquitin-Like Protein System; 5.8 Autophagosomes Formation; 5.9 Maturation of Autophagosomes to Autolysosomes; 5.10 Autophagy as a Process of Cell Death , 5.11 Autophagy Induction5.12 Autophagy and Cancer; 5.13 Inhibition of Autophagy; 5.14 Autophagy Activation; References; Chapter 6: Oncosis; List of Abbreviations; 6.1 Molecular Mechanisms of Oncosis Process; 6.2 Oncosis in Human Pathology; References; Chapter 7: Necrosis; List of Abbreviations; 7.1 Processes Leading to Cell Death; 7.2 Accidental Cell Death and Necrosis; 7.3 Does Programmed Necrotic Cell Death Exist?; 7.4 Relationships of Apoptosis and Necrosis; 7.5 Relationships Between Autophagy and Necrosis; 7.6 Molecular Mechanisms of Necrosis; References , Part III Process of Cell Death Embryonic OvaryChapter 8: Programmed Cell Death in Fetal Oocytes; 8.1 Introduction; 8.2 Defining the Form/s of Fetal Oocyte Death; 8.2.1 In Vivo Studies; 8.2.2 In Vitro Studies; 8.3 Growth Factor-Regulated Oocyte Death; 8.3.1 Apoptotic and Autophagic Pathways; 8.3.2 Bcl-x Family Members and Caspases; 8.4 Quality Control-Dependent Oocyte Death; 8.4.1 Crossover Defects as Possible Cause of Oocyte Elimination; 8.4.2 Oocyte Cysts and Self Sacrifice; 8.5 Conclusions; References; Chapter 9: DNA Damage and Apoptosis in Fetal and Ovarian Reserve Oocytes , 9.1 Synopsis of Oocyte Development and Establishment of the Oocyte Reserve
    Weitere Ausg.: ISBN 9789400711334
    Weitere Ausg.: Buchausg. u.d.T. ISBN 978-94-007-1133-4
    Sprache: Englisch
    Schlagwort(e): Säugetiere ; Eierstock ; Zelltod
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 2
    UID:
    almahu_9949419308902882
    Umfang: VI, 235 p. , online resource.
    Ausgabe: 1st ed. 2011.
    ISBN: 9789400711341
    Inhalt: The ovary is a suitable organ for studying the processes of cell death. Cell death was first described in the rabbit ovary (Graaffian follicles), the phenomenon being called 'chromatolysis'. To date, it is recognized that various forms of cell death (programmed cell death, apoptosis and autophagy) are essential components of ovarian development and function. Programmed cell death is responsable for the ovarian endowment of primordial follicles around birth; in the prepuberal and adult period, apoptosis is a basic mechanism by which oocytes are eliminated by cancer therapies and environmental toxicants; in the ovarian cycle, follicular atresia and luteal regression involve follicular cell apoptosis. Finally, abnormalities in cell death processes may lead to ovarian disease such as cancer and chemoresistance. In this book, after an introductory description of various forms of cell death and of the ovary development and function in mammals, the processes of cell death in ovarian somatic cells and oocytes are described at cytological, physiological and molecular levels and analyzed in the embryonic, prepuberal and adult ovary. A complex array of molecular pathways triggered by extrinsic and intrinsic signals able tor induce or suppress cell death in the same cell, according to cell type and ovary developmental stage, emerges. Physiological interactions with the axis hypothalamus-hypophysis as well as ovarian internal functional signal are also critically reviewed to explain the abortive development of follicles before the beginning of the ovarian cycle. The book conveys information useful to the updating of biologists and physicians who are interested to the ovary biology and functions. Hopefully it should provide also clues for stimulating novel experiments in the study of cell death in the mammalian ovary still at an early stage.
    In: Springer Nature eBook
    Weitere Ausg.: Printed edition: ISBN 9789400793941
    Weitere Ausg.: Printed edition: ISBN 9789400711334
    Weitere Ausg.: Printed edition: ISBN 9789400711358
    Sprache: Englisch
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
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  • 3
    Buch
    Buch
    Dordrecht [u.a.] : Springer-Verlag
    UID:
    kobvindex_ZLB15362493
    Umfang: VI, 235 Seiten , Ill.
    ISBN: 9789400711334
    Anmerkung: Text engl.
    Sprache: Englisch
    Schlagwort(e): Zelltod ; Eierstock
    Bibliothek Standort Signatur Band/Heft/Jahr Verfügbarkeit
    BibTip Andere fanden auch interessant ...
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