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  • 1
    Online Resource
    Online Resource
    Dordrecht : Springer Science+Business Media B.V
    UID:
    gbv_165128914X
    Format: Online-Ressource (XVIII, 282p. 24 illus., 21 illus. in color, digital)
    ISBN: 9789400712171
    Series Statement: Subcellular Biochemistry 55
    Content: The book contains contributions by leading figures in philosophy of mind and action, emotion theory, and phenomenology. As the focus of the volume is truly innovative we expect the book to sell well to both philosophers and scholars from neighboring fields such as social and cognitive science. The predominant view in analytic philosophy is that an ability for self-evaluation is constitutive for agency and intentionality. Until now, the debate is limited in two (possibly mutually related) ways: Firstly, self-evaluation is usually discussed in individual terms, and, as such, not sufficiently related to its social dimensions, secondly, self-evaluation is viewed as a matter of belief and desire, neglecting its affective and emotional aspects. The aim of the book is to fill these research lacunas and to investigate the question of how these two shortcomings of the received views are related.
    Note: Includes bibliographical references and index , CONTENTS; 1 Nucleotide Release by Airway Epithelia; 2 Mechanisms Regulating Airway Nucleotides; 3 Computational Model for the Regulation of ExtracellularATP and Adenosine in Airway Epithelia; 4 Regulation of Airway Nucleotides in Chronic Lung Diseases; 5 Nucleotide-Mediated Airway Clearance; 6 Purinergic Signaling in Wound Healingand Airway Remodeling; 7 Purinergic Regulation of Airway Inflammation; 8 Animal Models of Airway Diseases; 9 Therapeutic Applications; Index
    Additional Edition: ISBN 9789400712164
    Additional Edition: Buchausg. u.d.T. Purinergic regulation of respiratory diseases Dordrecht [u.a.] : Springer, 2011 ISBN 9789400712164
    Language: English
    Subjects: Biology
    RVK:
    Keywords: Atemwegskrankheit ; Purin-Nucleotid-Stoffwechsel ; Regulation
    URL: Volltext  (lizenzpflichtig)
    URL: Cover
    Library Location Call Number Volume/Issue/Year Availability
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  • 2
    UID:
    almahu_9949419313302882
    Format: XVIII, 282 p. , online resource.
    Edition: 1st ed. 2011.
    ISBN: 9789400712171
    Series Statement: Subcellular Biochemistry, 55
    Content: We proudly present the first book to integrate all aspects of purinergic signaling in the respiratory system. The first chapters introduce basic notions of purinergic pharmacology and metabolism, which allows readers from all scientific backgrounds to fully grasp the importance of these signaling networks for airway defenses, including mucociliary clearance and inflammatory responses. Then, chapters are devoted to the groundbreaking discovery that chronic respiratory diseases, including asthma, cystic fibrosis and chronic obstructive pulmonary disease (COPD), present specific aberrances in purinergic signaling which essentially drive lung complications. The last chapters describe the animal models used to investigate purinergic signaling in respiratory diseases, and the therapeutic applications developed by the pharmaceutical industry based on receptor agonists/antagonists and metabolic correctors. This highly comprehensive manuscript constitutes an invaluable tool for beginners and experts to follow the rapidly evolving research field of purinergic signaling. Furthermore, the critical analysis of past clinical protocols should facilitate the identification of potent therapeutic targets, and provide a better understanding of the data acquired in current clinical trials.
    Note: Dedication. Preface -- Chapter 1. Nucleotide Release by Airway Epithelia -- Chapter 2. Mechanisms Regulating Airway Nucleotides -- Chapter 3. Computational Model for the Regulation of Extracellular ATP and Adenosine in Airway Epithelia -- Chapter 4. Regulation of Airway Nucleotides in Chronic Lung Diseases -- Chapter 5. Nucleotide-Mediated Airway Clearance -- Chapter 6. Purinergic Signaling in Wound Healing and Airway Remodeling -- Chapter 7. Purinergic Regulation of Airway Inflammation -- Chapter 8. Animal Models of Airway Diseases -- Chapter 9. Therapeutic Applications. Index.
    In: Springer Nature eBook
    Additional Edition: Printed edition: ISBN 9789400736061
    Additional Edition: Printed edition: ISBN 9789400712164
    Additional Edition: Printed edition: ISBN 9789400712188
    Language: English
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  • 3
    Book
    Book
    Dordrecht [u.a.] : Springer-Verlag
    UID:
    kobvindex_ZLB15414625
    Format: XVII, 280 Seiten , Ill., graph. Darst.
    ISBN: 9789400712164
    Series Statement: Subcellular biochemistry 55
    Note: Text engl.
    Language: English
    Keywords: Atemwegskrankheit ; Regulation ; Aufsatzsammlung ; Aufsatzsammlung ; Aufsatzsammlung
    Library Location Call Number Volume/Issue/Year Availability
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