In:
Advanced Synthesis & Catalysis, Wiley, Vol. 359, No. 13 ( 2017-07-03), p. 2316-2321
Abstract:
Enantioselective synthesis of chiral quinazoline‐based heterocycles is achieved through a chiral phosphine‐catalyzed [3+3] annulation reaction of quinazoline‐based 1,3‐dipoles with Morita−Baylis−Hillman carbonates. The reaction proceeds smoothly under mild conditions to give various chiral heterocyclic compounds in high yields with excellent diastereoselectivities and enantioselectivities. Further diverse elaborations of the annulation products work well to produce novel tetrahydroquinazoline derivatives. magnified image
Type of Medium:
Online Resource
ISSN:
1615-4150
,
1615-4169
DOI:
10.1002/adsc.v359.13
DOI:
10.1002/adsc.201601434
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2041384-1
detail.hit.zdb_id:
2033084-4