In:
American Journal of Hematology, Wiley, Vol. 47, No. 2 ( 1994-10), p. 69-73
Abstract:
Blood lymphocytes from patients with eosinophilia are known to produce interleukin‐5 (IL‐5) with appropriate stimulation in vitro. To determine whether blood lymphocytes from these patients produce IL‐5 in vivo, we tested the IL‐5 mRNA expression in blood lymphocytes immediately after separation by reverse‐transcriptase polymerase chain reaction (RT‐PCR) method. We found that lymphocytes from eosinophilic patients expressed IL‐5 mRNA, but lymphocytes from normal volunteers did not express the lymphokine. These findings suggest that in patients with eosinophilia, peripheral blood lymphocytes produce IL‐5 in vivo. © 1994 Wiley‐Liss, Inc.
Type of Medium:
Online Resource
ISSN:
0361-8609
,
1096-8652
DOI:
10.1002/ajh.2830470202
Language:
English
Publisher:
Wiley
Publication Date:
1994
detail.hit.zdb_id:
1492749-4
