In:
Asian Journal of Organic Chemistry, Wiley, Vol. 10, No. 11 ( 2021-11), p. 3028-3033
Abstract:
PR 3 efficiently catalyzes the addition of H‐spirophosphorane to electron‐deficient alkenes to give the spirophosphoranes with a pentacoordinate P−C bond in moderate to excellent yields. This practical procedure was conducted by using PR 3 as an organocatalyst, which avoided the use of an additional base, traditional heating, and metal reagents. The investigation of the reaction mechanism showed that the zwitterion intermediate served as the base to further catalyze hydrospirophosphorane. Then the spirophosphoranide formed as a nucleophile attacked electron‐deficient alkene to give the addition products. This reaction is a first and simple hydrophosphorylation reaction of alkenes to construct pentacoordinate P−C bond under organocatalysis
Type of Medium:
Online Resource
ISSN:
2193-5807
,
2193-5815
DOI:
10.1002/ajoc.202100536
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2679333-7