In:
Asian Journal of Organic Chemistry, Wiley, Vol. 11, No. 1 ( 2022-01)
Abstract:
The first facile and efficient palladium‐catalyzed selective hydroamination of aliphatic alkenes with hydrazides as nitrogen‐based reaction partners has been described. This method provides a divergent and regioselective access to a variety of γ‐ and δ‐hydrazide substituted amide derivatives. The 8‐aminoquinolyl directing group could be readily removed to afford the corresponding γ‐ and δ‐hydrazide substituted carboxylic acid derivatives that are commonly seen in drug molecules and other bioactive compounds.
Type of Medium:
Online Resource
ISSN:
2193-5807
,
2193-5815
DOI:
10.1002/ajoc.202100742
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
2679333-7