In:
Angewandte Chemie International Edition, Wiley, Vol. 57, No. 25 ( 2018-06-18), p. 7385-7389
Abstract:
The point‐of‐care testing concept has been exploited to design and develop portable and cheap bioanalytical systems that can be used on‐site by conservators. These systems employ lateral flow immunoassays to simultaneously detect two proteins (ovalbumin and collagen) in artworks. For an in‐depth study on the application of these portable biosensors, both chemiluminescent and colorimetric detections were developed and compared in terms of sensitivity and feasibility. The chemiluminescent system displayed the best analytical performance (that is, two orders of magnitude lower limits of detection than the colorimetric system). To simplify its use, a disposable cartridge was designed ad hoc for this specific application. These results highlight the enormous potential of these inexpensive, easy‐to‐use, and minimally invasive diagnostic tools for conservators in the cultural heritage field.
Type of Medium:
Online Resource
ISSN:
1433-7851
,
1521-3773
DOI:
10.1002/anie.201713298
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2011836-3
detail.hit.zdb_id:
123227-7