In:
Bulletin of the Korean Chemical Society, Wiley, Vol. 37, No. 7 ( 2016-07), p. 1086-1094
Kurzfassung:
We have developed liposomes modified with various surface‐charged lipids in order to solubilize the new algicidal agent, N ‐[(3,4‐dichlorophenyl)methyl]cyclohexanamine ( DP92 ), and enhance its algicidal activity against harmful algal blooms ( HABs ). The effect of liposome surface charge on algicidal activity was evaluated by using positively charged and neutral liposomes. The algicidal activity of the developed liposomes was evaluated by monitoring the inhibition of the growth rates of HABs ( Heterosigma circularisquama ( HC ) and Heterosigma akashiwo ( HA )). The algicidal activity of the liposomes was 2–6 times stronger compared to that of control. The solubilization of DP92 by entrapment in liposomes increased the solubility of DP92 and improved its algicidal activity up to sixfold. The electrostatic interaction between the negatively charged cell walls of HABs and the cationic liposomes additionally enhanced the algicidal activity of DP92 .
Materialart:
Online-Ressource
ISSN:
1229-5949
,
1229-5949
DOI:
10.1002/bkcs.2016.37.issue-7
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2016
ZDB Id:
2056474-0
