In:
Chemistry & Biodiversity, Wiley, Vol. 15, No. 7 ( 2018-07)
Abstract:
Two new flavonoid glucuronate esters, named scuregeliosides A and B ( 1 and 2 ), as well as three known ones, chrysin‐7‐ O‐β ‐ d ‐glucuronic acid methyl ester ( 3 ), 5,7,4′‐trihydroxyflavone‐8‐ O‐β ‐ d ‐glucuronic acid methyl ester ( 4 ) and apigenin‐7 ‐O‐β ‐ d ‐glucuronic acid ethyl ester ( 5 ), were isolated from the ethanolic extract of the whole plant of Scutellaria regeliana . Their chemical structures were elucidated on the basis of comprehensive spectroscopic analyses. Five compounds were screened for anti‐inflammatory activity in vitro . As the results, the inhibition rates of release of β ‐glucuronidase from rat polymorphonuclear leukocytes were in the range of 42.2 – 47.1% at a concentration of 10 μ m .
Type of Medium:
Online Resource
ISSN:
1612-1872
,
1612-1880
DOI:
10.1002/cbdv.201800038
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
2139001-0
SSG:
12