In:
Chemistry & Biodiversity, Wiley, Vol. 19, No. 9 ( 2022-09)
Abstract:
(±)‐Involucrasin C ( 1 ), a pair of new 2,3‐dihydro‐1 H ‐indene enantiomers, along with an enantiomeric analog ( 2 ), were isolated from Shuteria involucrata . Their structures were established by the basis of comprehensive spectroscopic data analysis and X‐ray crystallographic diffraction. Both 1 and 2 significantly inhibited the secretion of pro‐inflammatory cytokines IL‐6, TNF‐ α , and IL‐1 β , suggesting that these two natural 2,3‐dihydro‐1 H ‐indene derivatives may be active components of S. involucrata and may block inflammation in the initial stage.
Type of Medium:
Online Resource
ISSN:
1612-1872
,
1612-1880
DOI:
10.1002/cbdv.202200188
Language:
English
Publisher:
Wiley
Publication Date:
2022
detail.hit.zdb_id:
2139001-0
SSG:
12
