In:
ChemCatChem, Wiley, Vol. 13, No. 5 ( 2021-03-05), p. 1383-1388
Abstract:
Amines are a ubiquitous class of compounds found in a variety of functional organic building blocks. Within the past years, hydrogen autotransfer catalysis has evolved as a new concept for the synthesis of amines. A through understanding of the mechanism of these reactions is necessary to design optimal catalysts. We investigate secondary amine formation catalyzed by a NNNN(P)Ru‐complex and provide understanding on the three reaction steps involved. We find that the ligand has to open one coordination site in order to allow the formation of a metal hydride intermediate. In a second step, a condensation reaction, which could also happen uncatalyzed in solution, is significantly enhanced by the presence of the ruthenium complex. The back‐transfer of the hydride to the substrate in a third step regenerates the catalyst.
Type of Medium:
Online Resource
ISSN:
1867-3880
,
1867-3899
DOI:
10.1002/cctc.202001588
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2501161-3