In:
Chemistry – A European Journal, Wiley, Vol. 10, No. 15 ( 2004-08-06), p. 3606-3614
Abstract:
A novel reaction for the introduction of an azide moiety by means of a mild radical process is currently under development. Sulfonyl azides are suitable azidating agents for nucleophilic radicals, such as secondary and tertiary alkyl radicals. More electrophilic radicals, such as enolate radicals, do not react with sulfonyl azides. This feature allowed the development of efficient intra‐ and intermolecular carboazidations of olefins. Due to the versatility of the azido group, this reaction has an important synthetic potential, as already demonstrated by the preparation of the core of several alkaloids, particularly those containing an amino‐substituted quaternary carbon center, such as FR901483.
Type of Medium:
Online Resource
ISSN:
0947-6539
,
1521-3765
DOI:
10.1002/chem.200400027
Language:
English
Publisher:
Wiley
Publication Date:
2004
detail.hit.zdb_id:
1478547-X