In:
Chemie in unserer Zeit, Wiley, Vol. 51, No. 6 ( 2017-12), p. 392-400
Abstract:
In this article we first discuss the NMR pulse sequence HMBC (heteronuclear multiple bond correlation) and demonstrate its importance for the final structure verification of the natural product cytisine. The 1 H‐, 13 C‐, COSY‐ und HSQC‐spectra of this compound have been shown in the first two articles of this series. After this we explain the physics of the NOESY‐experiment (nuclear Overhauser effect spectroscopy) and apply this for the stereochemical assignment of the proton signals. A correlation diagram between NOE integrals and hydrogen atom distances proofs the correct analysis.
Type of Medium:
Online Resource
ISSN:
0009-2851
,
1521-3781
DOI:
10.1002/ciuz.201700778
Language:
German
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2006650-8
detail.hit.zdb_id:
6904-8