In:
Chinese Journal of Chemistry, Wiley, Vol. 34, No. 7 ( 2016-07), p. 683-688
Abstract:
A novel total synthesis of Mansouramycin B ( 1 ) was performed via 10 steps in 28% overall yield starting from the readily available and cheap salicylaldehyde. Two key steps of this total synthesis are noteworthy. The first one is base‐promoted one‐pot aerobic aromatization of N ‐tosyltetrahydroisoquinoline 6 , the second one is oxidation of 5‐hydroxy‐3‐methyl‐isoquinoline 8 with iodobenzene diacetate [PhI(OAc) 2 ].
Type of Medium:
Online Resource
ISSN:
1001-604X
,
1614-7065
DOI:
10.1002/cjoc.201600020
Language:
English
Publisher:
Wiley
Publication Date:
2016
detail.hit.zdb_id:
2144352-X
SSG:
6,25