In:
Cancer, Wiley, Vol. 123, No. 7 ( 2017-04), p. 1184-1193
Abstract:
Exome and/or targeted deep sequencing analysis of 10 primary cutaneous squamous cell carcinoma (cSCC) and 18 metastatic cSCC samples demonstrated mutations in known skin cancer‐related genes such as TP53 and NOTCH1 . Combining frequency data from primary and metastatic cSCCs from the current study with those in the literature demonstrated a higher mutation frequency in TP53 and KMT2D in metastatic tumors compared with nonmetastatic cSCC samples.
Type of Medium:
Online Resource
ISSN:
0008-543X
,
1097-0142
Language:
English
Publisher:
Wiley
Publication Date:
2017
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1479932-7
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2599218-1
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2594979-2
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1429-1