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The association between germline BRCA2 variants and sensitivity to platinum‐based chemotherapy among men with metastatic prostate cancer

Pomerantz, Mark M. ; Spisák, Sandor ; Jia, Li ; [weitere]

Wiley ; 2017

In: Cancer Vol. 123, No. 18 ( 2017-09-15), p. 3532-3539

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In: Cancer, Wiley, Vol. 123, No. 18 ( 2017-09-15), p. 3532-3539

Kurzfassung: Platinum‐based chemotherapy does not play a significant role in the management of advanced prostate cancer. In the current study, patients with metastatic castration‐resistant prostate cancer who have inherited pathogenic variants in BRCA2 appear to respond favorably to platinum‐based chemotherapy compared with those who do not carry an inherited BRCA2 variant. See also pages 3441‐4.

Materialart: Online-Ressource

ISSN: 0008-543X , 1097-0142

URL: Issue

URL: Article

DOI: 10.1002/cncr.v123.18

DOI: 10.1002/cncr.30808

Sprache: Englisch

Verlag: Wiley

Publikationsdatum: 2017

ZDB Id: 1479932-7

ZDB Id: 2599218-1

ZDB Id: 2594979-2