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Frequency and outcomes of brain metastases in patients with HER2 ‐mutant lung cancers

Offin, Michael ; Feldman, Daniel ; Ni, Ai ; [weitere]

Wiley ; 2019

In: Cancer Vol. 125, No. 24 ( 2019-12-15), p. 4380-4387

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In: Cancer, Wiley, Vol. 125, No. 24 ( 2019-12-15), p. 4380-4387

Kurzfassung: Oncogenic driver mutations influence the disease course, treatment options, and development of brain metastases in patients with lung cancers. Results from this retrospective analysis of 498 patients with HER2 ‐, KRAS ‐, or EGFR ‐mutant lung cancers show that patients with HER2 ‐driven lung cancers have reduced overall survival and are at increased risk for developing brain metastases while they are on treatment.

Materialart: Online-Ressource

ISSN: 0008-543X , 1097-0142

URL: Issue

URL: Article

DOI: 10.1002/cncr.v125.24

DOI: 10.1002/cncr.32461

Sprache: Englisch

Verlag: Wiley

Publikationsdatum: 2019

ZDB Id: 1479932-7

ZDB Id: 2599218-1

ZDB Id: 2594979-2