In:
Cancer, Wiley
Abstract:
Results from this multicenter study show that individuals with pancreatic cancer and a germline pathogenic variant in ATM , BRCA1 , BRCA2 , EPCAM , MLH1 , MSH2 , MSH6 , PALB2 , or PMS2 are more likely to have a family history of pancreatic cancer, especially a first‐degree relative, compared to individuals with pancreatic cancer and no germline pathogenic variant. However, most individuals diagnosed with pancreatic cancer who have a germline pathogenic variant in one of these genes would not have met current guidelines for pancreatic surveillance because of a lack of family history.
Type of Medium:
Online Resource
ISSN:
0008-543X
,
1097-0142
Language:
English
Publisher:
Wiley
Publication Date:
2024
detail.hit.zdb_id:
1479932-7
detail.hit.zdb_id:
1429-1