In:
European Journal of Organic Chemistry, Wiley, Vol. 2007, No. 2 ( 2007-01), p. 249-257
Kurzfassung:
The enantiomerically pure pyrrolidine diester 4 i s a useful building block for the synthesis of chiral hydroporphyrin compounds. Treatment of optically active aromatic amines with bislactone 5 gave pairs of N ‐alkylated lactam‐lactone diastereomers 6 and 8 . These diastereomers were separated by MPL chromatography and in the case of 8 they could be debenzylated to yield the enantiomerically pure lactam‐lactone 7 and its enantiomer. The (–)‐lactam‐lactone enantiomer 7 was further transformed into building block 4 .(© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2007)
Materialart:
Online-Ressource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2007:2
DOI:
10.1002/ejoc.200600656
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2007
ZDB Id:
1475010-7
