In:
European Journal of Organic Chemistry, Wiley, Vol. 2011, No. 28 ( 2011-10), p. 5423-5426
Abstract:
The ability of simple uracils to afford bis(uracil‐5‐yl)methanes upon reaction with paraformaldehyde is well documented. This reaction has been used in the preparation of pyrimidinophanes. The extension of the scope of this reaction to the synthesis of multipyrimidinophanes has been reported. Starting with isomeric pyrimidinophane containing 6‐methyluracil and 5‐methyluracil (thymine) moieties, linearly arranged multimacrocycles were prepared. A completely unexpected result was that the reactions of isomeric pyrimidinophanes containing 6‐methyluracil moieties with paraformaldehyde produced only cyclic‐arranged macrocycles, in particular, cryptand‐like pyrimidinophanes and multipyrimidinophanes with a cyclic topology.
Type of Medium:
Online Resource
ISSN:
1434-193X
,
1099-0690
DOI:
10.1002/ejoc.v2011.28
DOI:
10.1002/ejoc.201100985
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
1475010-7