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Nickel‐Catalyzed Aminofluoroalkylation of Alkenes: Access to Difluoroalkylated N ‐Containing Heterocyclic Compounds

Fu, Xiaoyi ; Zhang, Tianyu ; Wu, Jingjing ; [weitere]

Wiley ; 2022

In: European Journal of Organic Chemistry Vol. 2022, No. 1 ( 2022-01-11)

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In: European Journal of Organic Chemistry, Wiley, Vol. 2022, No. 1 ( 2022-01-11)

Kurzfassung: A nickel‐catalyzed aminofluoroalkylative cyclization of unactive alkenes with iododifluoromethyl ketones was developed to construct versatile difluoroalkylated Nitrogen‐containing heterocycles including aziridines, pyrrolidines and piperidines in moderate to high yields. This method features a broad substrate scope and has been demonstrated on gram scale.

Materialart: Online-Ressource

ISSN: 1434-193X , 1099-0690

URL: Issue

URL: Article

DOI: 10.1002/ejoc.v2022.1

DOI: 10.1002/ejoc.202101205

RVK:

VA 4073

Sprache: Englisch

Verlag: Wiley

Publikationsdatum: 2022

ZDB Id: 1475010-7