In:
International Journal of Geriatric Psychiatry, Wiley, Vol. 34, No. 2 ( 2019-02), p. 369-377
Abstract:
The frontal lobe hypothesis of age‐related cognitive decline suggests that the deterioration of the prefrontal cortical regions that occurs with aging leads to executive function deficits. Photobiomodulation (PBM) is a newly developed, noninvasive technique for enhancing brain function, which has shown promising effects on cognitive function in both animals and humans. This randomized, sham‐controlled study sought to examine the effects of PBM on the frontal brain function of older adults. Methods/designs Thirty older adults without a neuropsychiatric history performed cognitive tests of frontal function (ie, the Eriksen flanker and category fluency tests) before and after a single 7.5‐minute session of real or sham PBM. The PBM device consisted of three separate light‐emitting diode cluster heads (633 and 870 nm), which were applied to both sides of the forehead and posterior midline, and delivered a total energy of 1349 J. Results Significant group (experimental, control) × time (pre‐PBM, post‐PBM) interactions were found for the flanker and category fluency test scores. Specifically, only the older adults who received real PBM exhibited significant improvements in their action selection, inhibition ability, and mental flexibility after vs before PBM. Conclusions Our findings support that PBM may enhance the frontal brain functions of older adults in a safe and cost‐effective manner.
Type of Medium:
Online Resource
ISSN:
0885-6230
,
1099-1166
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
1500455-7
