In:
Head & Neck, Wiley, Vol. 33, No. 3 ( 2011-03), p. 324-329
Abstract:
Cystic lymph node metastasis (CLNM) is commonly found in human papillomavirus (HPV)‐associated tonsillar squamous cell carcinoma (SCC). The aim of this study was to compare the accuracy in detecting cystic lymph node metastasis from tonsillar SCC between contrast‐enhanced CT, 18 F‐ fluorodeoxyglucose‐positron emission tomography (FDG‐PET), non‐enhanced 18 F‐FDG‐PET/CT, and contrast‐enhanced 18 F‐FDG‐PET/CT. Methods. Thirty‐four patients with a tonsillar SCC undergoing a pretreatment contrast‐enhanced 18 F‐FDG‐PET/CT followed by a neck dissection as a standard of reference were included. The contrast‐enhanced CT part, the 18 F‐FDG‐PET part, the non‐enhanced 18 F‐FDG‐PET/CT part, and the contrast‐enhanced 18 F‐FDG‐PET/CT were assessed separately for correct N classification and the differentiation of N0 versus N+. Results. Contrast‐enhanced 18 F‐FDG‐PET/CT, non‐enhanced 18 F‐FDG‐PET/CT, and contrast‐enhanced CT are equally accurate for correct neck staging. Regarding pN0 versus pN+, contrast‐enhanced CT and contrast‐enhanced 18 F‐FDG‐PET/CT are superior to non‐enhanced 18 F‐FDG‐PET/CT ( p = .017). Conclusion. Contrast‐enhanced CT and contrast‐enhanced 18 F‐FDG‐PET/CT perform equally and better than non‐enhanced 18 F‐FDG‐PET/CT in detecting CLNM in tonsillar SCC. Therefore, in patients scheduled for 18 F‐FDG‐PET/CT, we strongly suggest performing a contrast‐enhanced 18 F‐FDG‐PET/CT, which is not routine in most centers. © 2010 Wiley Periodicals, Inc. Head Neck, 2010
Type of Medium:
Online Resource
ISSN:
1043-3074
,
1097-0347
Language:
English
Publisher:
Wiley
Publication Date:
2011
detail.hit.zdb_id:
2001440-5
