In:
International Journal of Cancer, Wiley, Vol. 133, No. 12 ( 2013-12-15), p. 2843-2851
Kurzfassung:
What's new? The critical role of thyroperoxidase (TPO) in thyroid function is evident by its mutation, which is a common cause of congenital hypothyroidism. Its mutation has also been implicated in thyroid cancer, a hypothesis that gains new support with this study, in which two TPO genetic variants, rs2048722 and rs732609, were linked to risk of differentiated thyroid cancer in a European study population. Among Italian patients, a negative association was identified for both variants, while for Spanish patients, a positive association was found. The association patterns suggest a role for population‐specific factors in thyroid cancer.
Materialart:
Online-Ressource
ISSN:
0020-7136
,
1097-0215
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2013
ZDB Id:
218257-9
ZDB Id:
1474822-8
