In:
International Journal of Cancer, Wiley, Vol. 136, No. 5 ( 2015-03), p. 1228-1233
Abstract:
What's new? Circulating tumor cells (CTCs) enter the circulation after being shed by primary tumors, making them potential markers in the diagnosis of cancer. However, methods to detect CTCs are in need of refinement. In an attempt to improve CTC identification in pancreatic cancer, the authors of this study examined the detection potential of a combination of methods, including immunostaining, fluorescence in situ hybridization with the centromere of chromosome 8 (CEP8) probe method. Enriched cell populations were classified into five patterns, including patterns for cytokeratin‐positive or ‐negative CTCs and diploid or hyperdiploid CTCs, warranting further investigation of CTC characteristics.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2015
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8