In:
International Journal of Cancer, Wiley, Vol. 140, No. 1 ( 2017-01), p. 86-94
Abstract:
What's new? Recent genome‐wide association studies (GWAS) have identified a number of genetic variations that are associated with colorectal cancer (CRC), including several single nucleotide polymorphisms (SNPs). However, copy number variations (CNVs) associated with CRC risk have not been extensively analyzed. In this study, the authors found that a common CNV called PKD1L2 is strongly associated with CRC, especially in young and obese individuals. This and other CNVs may thus enhance screening protocols for CRC, especially among younger adults.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8