In:
International Journal of Cancer, Wiley, Vol. 145, No. 7 ( 2019-10), p. 1768-1773
Kurzfassung:
What's new? While breast density is a strong predictor of breast cancer risk, little is known about the molecular mechanisms that determine breast density and their influence on cancer risk. Here, in women aged 40 to 70 in two Australian study cohorts, including one twin cohort, genome‐wide association analysis was used to investigate relationships between DNA methylation and mammographic density measures that predict breast cancer. DNA methylation assessed from peripheral blood and conventional mammographic density measures were not significantly associated. Moreover, no associations were detected between breast density measures and DNA methylation at genetic loci known to be associated with mammographic density.
Materialart:
Online-Ressource
ISSN:
0020-7136
,
1097-0215
Sprache:
Englisch
Verlag:
Wiley
Publikationsdatum:
2019
ZDB Id:
218257-9
ZDB Id:
1474822-8
