In:
International Journal of Cancer, Wiley, Vol. 145, No. 9 ( 2019-11), p. 2427-2432
Abstract:
What's new? Genetic variants associated with colorectal cancer (CRC) risk potentially also exert effects on disease prognosis, though little is known about the heritability of CRC survival. In this population‐based study, genetic variants of CRC susceptibility were investigated for their relevance in CRC survival based on analyses of variants identified in genome‐wide association studies (GWASs). Nonsignificant associations were detected between small numbers of genetic variants and overall survival and CRC‐specific survival. Overall, the findings do not support the existence of prognostic effects of common CRC risk variants. Rather, CRC survival may have distinct genetic determinants, warranting separate investigation by GWAS.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8