In:
International Journal of Cancer, Wiley, Vol. 147, No. 3 ( 2020-08), p. 662-668
Abstract:
What's new? Only a small fraction of early‐onset childhood cancers are linked to hereditary factors, suggesting that perinatal exposures, particularly in the mother, significantly impact childhood cancer risk. A potentially important, though understudied risk factor is maternal diabetes. This investigation of nationwide population‐based registry data shows that maternal diabetes is associated with an elevated risk of childhood cancer in offspring. Offspring born to mothers diagnosed with gestational diabetes were at increased risk of childhood leukemia and certain solid tumors in particular. Further investigation is needed to determine whether diabetes medications taken during pregnancy can reduce cancer risk in offspring.
Type of Medium:
Online Resource
ISSN:
0020-7136
,
1097-0215
Language:
English
Publisher:
Wiley
Publication Date:
2020
detail.hit.zdb_id:
218257-9
detail.hit.zdb_id:
1474822-8