In:
Israel Journal of Chemistry, Wiley, Vol. 61, No. 11-12 ( 2021-12), p. 863-872
Abstract:
A semi‐symmetric vestige of an RNA apparatus with stereochemically controlled ribozyme capabilities is embedded and functions as the site of peptide bond formation within all contemporary ribosomes, a finding that is in line with Lahav and Leiserowitz earlier discoveries on stereochemically controlled chemical reactions. As the structure of this semi‐symmetrical self‐folded RNA entity is almost fully conserved in all known ribosomes, it seems to be resilient to evolution, thus hinting at its pre‐biotic origin and hence, suggested by us, to be the protoribosome. Recent studies, described shortly below, demonstrated peptide bond formation by the laboratory‐designed protoribosomes, which supports the notion that a pre‐biotic bonding entity is still functioning in all contemporary ribosomes.
Type of Medium:
Online Resource
ISSN:
0021-2148
,
1869-5868
DOI:
10.1002/ijch.v61.11-12
DOI:
10.1002/ijch.202100054
Language:
English
Publisher:
Wiley
Publication Date:
2021
detail.hit.zdb_id:
2066481-3