In:
Journal of Applied Toxicology, Wiley, Vol. 39, No. 5 ( 2019-05), p. 735-750
Abstract:
• Cellular uptake and localization of ZnO nanoparticles were assessed. • Ultrastructural modifications and morphological changes in cells were observed. • ZnO nanoparticles induced oxidative stress and HGPRT gene mutation in V‐79 cells. • Cell cycle changes and apoptosis induced cell death in V‐79 cells were also investigated. • V‐79 cells are a better model for mutagenicity assessment than the prokaryotic model.
Type of Medium:
Online Resource
ISSN:
0260-437X
,
1099-1263
Language:
English
Publisher:
Wiley
Publication Date:
2019
detail.hit.zdb_id:
1475015-6