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    In: Journal of Ultrasound in Medicine, Wiley, Vol. 41, No. 7 ( 2022-07), p. 1763-1771
    Abstract: To compare the prevalence and size of residual niche in the nongravid uterus following Cesarean delivery (CD) with different hysterotomy closure techniques (HCTs). METHODS Saline infusion sonohysterogram (SIS) was performed in women after one prior CD, documenting the presence or absence of a postoperative niche and measuring its depth, width, length, and residual myometrial thickness. Women were grouped by HCT: Technique A (endometrium‐free) and Technique B (routine non‐endometrium‐free). The primary outcome was the prevalence of a clinically significant niche, defined as a depth of 〉 2 mm. HCT groups were compared using χ 2 , T ‐test (ANOVA), and analyzed using logistic regression and two‐sided test ( P   〈  .05). RESULTS Forty‐five women had SIS performed, 25 and 20 via Technique A and B, respectively. Technique groups varied by average interval time from CD to SIS (13.6 versus 74.5 months, P  = 0.006) but were otherwise similar. Twenty niches were diagnosed, 85% of which were clinically significant, including five following Technique A, nine following Technique B with double‐layer closure, and three following Technique B with single‐layer ( P  = .018). The average niche depth was 2.4 mm and 4.9 mm among the two‐layer subgroups following Techniques A and B, respectively ( P  = .005). A clinically significant niche development was six times higher with Technique B when compared to Technique A (OR 6.0, 95% CI 1.6–22.6, P  = .008); this significance persisted after controlling for SIS interval on multivariate analysis (OR 4.4, 95% CI 1.1–18.3, P  = .04). The average niche depth was 5.7 ± 2.9 mm following Technique B with single‐layer. CONCLUSION Hysterotomy closure techniques determine the prevalence of post‐Cesarean delivery niche formation and size. Exclusion of the endometrium at uterine closure reduces the development of significant scar defects.
    Type of Medium: Online Resource
    ISSN: 0278-4297 , 1550-9613
    URL: Issue
    Language: English
    Publisher: Wiley
    Publication Date: 2022
    detail.hit.zdb_id: 2067124-6
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