In:
Macromolecular Symposia, Wiley, Vol. 294, No. 1 ( 2010-08), p. 109-119
Abstract:
The treatment of bone and cartilage defects with bioengineered constructs of artificial scaffolds and autogenous cells became the main challenge of contemporary regenerative medicine. Early defect repair may prevent secondary injury. Recent studies could prove that bone and cartilage cells are sensitive to microscale and nanoscale patterns of surface topography and chemical structure. Nanostructured materials provide an environment for tissue regeneration mimicking the physiological range of extracellular matrix. The article reviews several studies substantiating the superiority of nanostructured materials for bone and cartilage repair along with own results on cell attachment.
Type of Medium:
Online Resource
ISSN:
1022-1360
,
1521-3900
DOI:
10.1002/masy.201050810
Language:
English
Publisher:
Wiley
Publication Date:
2010
detail.hit.zdb_id:
2038549-3