In:
Pediatric Blood & Cancer, Wiley, Vol. 64, No. 9 ( 2017-09)
Abstract:
Hispanics with acute leukemias have poorer outcomes than non‐Hispanic whites (NHWs), despite an increased likelihood of favorable prognostic features. We reviewed medical records from 167 children ages 0–18 years diagnosed with de novo AML over an 18‐year period at Texas Children's Cancer Center, among whom 129 self‐identified as Hispanic or NHW. Although Hispanics were significantly more likely to have the favorable prognostic cytogenetic feature t(8;21) ( P = 0.04), the expected survival benefit was not observed. This lack of survival benefit was primarily due to significantly poorer event‐free and overall survival among Hispanics treated with upfront stem cell transplantation after achieving first clinical remission ( P = 0.008).
Type of Medium:
Online Resource
ISSN:
1545-5009
,
1545-5017
Language:
English
Publisher:
Wiley
Publication Date:
2017
detail.hit.zdb_id:
2130978-4