In:
Prenatal Diagnosis, Wiley, Vol. 38, No. 13 ( 2018-12), p. 1120-1128
Abstract:
What's already known about this topic? In 5%‐10% of pregnancies with a fetal structural anomaly and in 0.5%‐2% of pregnancies without ultrasound anomalies, CMA reveals cryptic, clinically relevant CNVs. What does this study add? This manuscript describes the establishment of a national database for prenatal microarray results in Belgium. This database, which is one of the largest currently available, allows: calculation of added values of microarray over karyotyping for different categories of indications; determination of the most common syndromes, incidental findings, and susceptibility CNVs in the Belgian prenatal population; evaluation of our national reporting policy; and reflection on the effect of the implementation of NIPT.
Type of Medium:
Online Resource
ISSN:
0197-3851
,
1097-0223
Language:
English
Publisher:
Wiley
Publication Date:
2018
detail.hit.zdb_id:
1491217-X