In:
Journal of Polymer Science Part A: Polymer Chemistry, Wiley, Vol. 47, No. 11 ( 2009-06), p. 2763-2773
Abstract:
A series of poly( N ‐isopropylacrylamide‐ co ‐ N ‐hydroxymethylacrylamide) P(NIPAM‐ co ‐NHMA) copolymers were firstly synthesized via free radical polymerization. Then, the hydrophobic, photosensitive 2‐diazo‐1,2‐naphthoquinone (DNQ) molecules were partially and randomly grafted onto P(NIPAM‐ co ‐NHMA) backbone through esterification to obtain a triple‐stimuli (photo/pH/thermo) responsive copolymers of P(NIPAM‐ co ‐NHMA‐ co ‐DNQMA). UV‐vis spectra showed that the lower critical solution temperature (LCST) of P(NIPAM‐ co ‐NHMA) ascended with increasing hydrophilic comonomer NHMA molar fraction and can be tailored by pH variation as well. The LCST of the P(NIPAM‐ co ‐NHMA) went down firstly after DNQ modification and subsequently shifted to higher value after UV irradiation. Meanwhile, the phase transition profile of P(NIPAM‐ co ‐NHMA‐ co ‐DNQMA) could be triggered by pH and UV light as expected. Thus, a triple‐stimuli responsive copolymer whose solution properties could be, respectively, modulated by temperature, light, and pH, has been achieved. These stimuli‐responsive properties should be very important for controlled release delivery system. © 2009 Wiley Periodicals, Inc. J Polym Sci Part A: Polym Chem 47: 2763–2773, 2009
Type of Medium:
Online Resource
ISSN:
0887-624X
,
1099-0518
Language:
English
Publisher:
Wiley
Publication Date:
2009
detail.hit.zdb_id:
3004641-5
detail.hit.zdb_id:
1473076-5